Effect of remote ischemic preconditioning on postoperative cognitive dysfunction in adult patients with general anesthesia: a meta-analysis

Table 2 Sensitivity analyses

Study excluded	OR/MD (95% CI)	I² (%)	P for Cochrane’s Q test	P for overall effect
Influence of RIPC on POCD
Gasparovic 2019	0.49 [0.29,0.84]	54	0.03	0.009
Hudetz 2015	0.59 [0.38,0.91]	36	0.13	0.02
Jing 2011	0.53 [0.32,0.89]	50	0.04	0.02
Joung 2013	0.44 [0.26,0.76]	51	0.04	0.003
Meybohm 2013	0.43 [0.23,0.77]	51	0.04	0.005
Meybohm 2018	0.42 [0.23,0.79]	52	0.04	0.007
Su 2009	0.57 [0.35,0.91]	43	0.08	0.02
Tao 2014	0.45 [0.26,0.78]	53	0.03	0.004
Zhang 2020	0.56 [0.34,0.91]	46	0.07	0.02
Zhou 2018	0.52 [0.30,0.89]	51	0.04	0.02
Influence of RIPC on surgery time
He 2017	−0.99 [−8.5,6.52]	54	0.04	0.8
Hudetz 2015	−2.43 [−7.68,2.82]	61	0.02	0.36
Jing 2011	−1.96 [−8.15,4.23]	60	0.02	0.53
Joung 2013	−3.18 [−8.18,1.82]	56	0.03	0.21
Wang 2021	−4.74 [−9.01, −0.47]	39	0.13	0.03
Zhang 2020	−2.79 [−7.95,2.38]	59	0.02	0.29
Zhou 2018	−1.8 [−5.09,1,49]	0	0.5	0.28
Zou 2013	−3.06 [−8.17,2.06]	57	0.03	0.24

OR odds ratio, MD mean difference, CI confidence interval, POCD postoperative cognitive dysfunction, RIPC remote ischemic preconditioning

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