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Fig. 3 | Journal of Cardiothoracic Surgery

Fig. 3

From: Nrf2/HO-1 signaling activation alleviates cigarette smoke-induced inflammation in chronic obstructive pulmonary disease by suppressing NLRP3-mediated pyroptosis

Fig. 3

The activated Nrf2/HO-1 pathway suppressed the pyroptosis in lung tissues of COPD mice. A IHC staining of the lung tissues revealed that the activated Nrf2/HO-1 pathway suppressed NLRP3 expression in COPD mice. B Western blot illustrated that the activated Nrf2/HO-1 pathway reduced the expression of pyroptosis-related proteins (Caspase-1 and GSDMD-N) in lung tissues of COPD mice. ***P < 0.001 vs. Control group. # P < 0.05 and ## P < 0.01 vs. COPD group

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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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