Clinical relevance of transcranial Doppler in a cardiac surgery setting: embolic load predicts difficult separation from cardiopulmonary bypass

Table 4 Multiple analysis of risk factors of difficult CPB separation and higher HITS

Multivariable analysis of difficult CPB separation
Risk factors	OR^a	95% CI	P value
Lower HITS category^b	0.687	0.299–1.576	0.376
Medium HITS category^b	0.253	0.109–0.584	0.001
Simple valve replacement^c	0.977	0.404–2.360	0.959
Coronary artery bypass graft with CPB^c	1.157	0.485–2.765	0.742
Cardiopulmonary bypass duration (min)	1.008	1.002–1.014	0.007
EuroSCORE II	1.179	1.083–1.284	< 0.001
Central venous pressure before CPB (mmHg)	1.082	1.005–1.164	0.037
Left ventricular ejection fraction superior to 50%	0.451	0.221–0.922	0.029
Age (year)	0.977	0.952–1.003	0.085

^aThe odds ratio is calculated for a difference of one additional unit for continuous variables
^bThe reference category is High HITS category
^cThe reference is the complex surgery
CI confidence interval, CPB cardiopulmonary bypass, EuroSCORE II European System for Cardiac Operative Risk Evaluation, HITS high-intensity transient signal, OR odds ratio

ISSN: 1749-8090