Diagnostic and prognostic value of plasma miR-106a-5p levels in patients with acute heart failure

Table 2 Comparative Analysis of Clinical Baseline Data

Characteristics	Control (n = 127)	AHF (n = 127)	P value
Age	61 (46,73)	62 (47,76)	0.535
Gender [Male, n (%)]	69 (54.33%)	74 (58.27%)	0.613
BMI (kg/m²)	25.57 ± 3.12	25.65 ± 2.97	0.834
Smoking [n (%)]	49 (38.58%)	54 (42.52%)	0.609
Alcohol consumption [n (%)]	60 (47.24%)	56 (44.09%)	0.706
Type 1 and 2 diabetes mellitus [n (%)]
Type 1	4 (19.05%)	4 (12.50%)	0.515
Type 2	17 (80.95%)	28 (87.50%)
Hypertension [n (%)]	58 (45.67%)	79 (62.20%)	0.012
SBP (mmHg)	121.08 ± 10.27	123.24 ± 12.86	0.140
DBP (mmHg)	75.14 ± 7.52	76.31 ± 7.65	0.220
LAD (mm)	36.42 ± 3.96	40.16 ± 4.87	< 0.001
LVEDD (mm)	47.73 ± 6.04	49.72 ± 4.61	0.004
LVEF (%)	61.18 ± 7.56	32.62 ± 5.74	< 0.001
NT-proBNP (pg/mL)	25.75 (16.60, 35.36)	102.97 (67.63, 156.34)	< 0.001
hs-CRP (mg/L)	5.18 (3.01, 7.12)	8.29 (4.30, 13.36)	< 0.001

Note AHF: acute heart failure; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; LAD: left atrium dimension; LVEDD: left ventricular end-diastolic diameter; LVEF: left ventricular ejection fraction; NT-proBNP: N-terminal pro-B type natriuretic peptide; hs-CRP: hypersensitive C-reactive protein. The Shapiro-Wilk test was used for normal distribution. Measurements that conformed to normal distribution were expressed as mean ± standard deviation and analyzed by independent samples t-test; data that did not conform to normal distribution were expressed as median (minimum, maximum) by Mann-Whitney test; categorical variables were expressed as n (%) by Fisher’s exact test. P < 0.05 indicated that the difference was statistically significant

ISSN: 1749-8090