Fig. 2

Image A shows an overview of the former tumor bed composed of necrotic tissue in the center (top left) surrounded by a rim of sparse fibrosis and a more prominent inflammatory infiltrate. At higher magnification (B), isolated structures such as indicated vessels and completely necrotic tumor nests can be seen within the necrosis zone (right). The adjacent transition zone between necrosis and normal lung tissue shows a high proportion of partially haemosiderin-laden macrophages and scattered lymphocytes