- Case report
- Open Access
- Open Peer Review
Beating heart mitral valve repair for a patient with previous coronary bypass: a case report and review of the literature
© Nakamura et al.; licensee BioMed Central Ltd. 2013
- Received: 4 May 2013
- Accepted: 25 August 2013
- Published: 30 August 2013
Mitral valve reoperation, through a median sternotomy, for a patient with patent coronary bypass grafts is technically challenging and carries higher postoperative morbidity and mortality than a primary operation. We present a case of mitral valve repair using a beating heart technique under normothermic cardiopulmonary bypass that was performed 3 years after a coronary artery bypass operation. A limited (10 cm) right thoracotomy was made and cardiopulmonary bypass was conducted using the ascending aortic and femoral venous cannulation. The left atrium was opened while beating was maintained. Triangular resection of the prolapsed portion of the posterior leaflet and ring annuloplasty were performed. Completeness of the repair was verified by direct visualization under beating condition and transesophageal echocardiogram. This technique is a safe and feasible option for a mitral valve reoperation that excludes re-sternotomy, extensive pericardial dissection and aortic clamping, thereby minimizes risks of bleeding, graft injury and myocardial damage.
- Mitral valve insufficiency
- Mitral valve repair
- Minimally invasive surgical procedures
The number of patients undergoing cardiac reoperations continues to increase. Redo procedures usually involve sternal reentry, which has the potential for hazardous injuries to the important structures and subsequent morbidity and mortality . In the case of a patient who has poor ventricular function for a long-standing valve disease, cardiac arrest may predispose the dilated myocardium to ischemia-reperfusion injury and postoperative low cardiac output . We describe a case in which we performed a redo mitral valve repair after coronary bypass surgery using a beating heart approach via a limited right thoracotomy. Advantages and disadvantages of the procedure are discussed.
Additional file 1: A transesophageal echocardiographic motion picture demonstrating no residual mitral regurgitation. (MP4 2 MB)
As techniques in cardiac surgery continue to improve and patients who have undergone surgeries live longer, the number of redo cardiac operation increases. Redo cardiac operations can be challenging because of an increasing rate of postoperative morbidity and mortality, which is particularly true in patients with previous coronary bypass . Techniques of mitral valve reoperation are becoming important because many patients have received mitral valve repair or bioprosthetic valve replacement over the last few decades, and these patients are prone to revisional operations down the road. In the present case, the patient had patent internal mammary grafts and a history of mediastinal wound infection. Intra-pericardial adhesion was expected to be dense, and it appeared quite difficult to re-enter the midline and dissect the internal mammary artery grafts. Therefore, the beating heart operation via a limited thoracotomy was a useful option as it avoided extensive dissection and injury to important structures [3, 4].
There are other options for a redo mitral repair: 1) sternotomy and cardioplegic arrest or 2) hypothermic fibrillatory arrest. Of these options, beating heart mitral valve repair via limited thoracotomy offers a number of advantages. First, continuous myocardial perfusion mitigates myocardial damage caused by ischemia-reperfusion injury . Although ventricular fibrillation is an alternative approach to avoid aortic clamping, it is known to reduce oxygen delivery to the subendocardium and result in suboptimal myocardial protection [2, 3]. Therefore, this approach would be helpful in patients with previous bypass surgeries who had dilated ventricles and functional mitral regurgitation due to progression of ischemic cardiomyopathy . As normothermic perfusion is maintained, risk of coagulopathy is reduced and blood loss is usually much less than with hypothermic fibrillatory arrest . By avoiding sternal reentry, risk of excessive blood loss and wound infection are minimized. Because pericardial dissection is limited to the left atrial incision, this approach is quite safe and timesaving. As is shown in the present case, physiological assessment of repair is easily made while beating is maintained . Finally, this approach can avoid systemic embolization caused by aortic clamping.
A major drawback of the approach is technical difficulties, especially in valve repair, while the heart is kept perfused and beating. Botta and colleagues reported 18 redo mitral valve cases with a similar approach; only 1 of 18 cases completed a valve repair; the remaining cases underwent valve replacement . To minimize the risk of compromising the quality of valve repair, it is quite important to maintain a relatively bloodless operative field, especially when aortic insufficiency is present. Although we used 2 drop-in suckers through the left atrial incision in this particular case, a left ventricular vent via the apex using mini-left thoracotomy was useful in our previous experience. Remifentanil  and Landiolol  were helpful for heart rate reduction to prevent regurgitant blood flow from coming up to the operative field. Another concern is the possibility of air embolism. Ricci and colleagues reported 59 cases of multiple valve surgery with beating condition; no neurological deficit that could have been caused by air embolism occurred . We believe that several points are important to preclude the possibility of air embolism. Also described elsewhere , a combination of vacuum-assisted venous drainage, carbon dioxide gas insufflation and aortic root venting can minimize the chance of air embolism. It is also important to keep the mitral valve incompetent to allow air bubbles to be ejected from the left ventricle. A saline injection test is never been applied because it would pressurize the ventricle. Furthermore, we routinely checked transesophageal echocardiogram before opening the left atrium and verified complete closure of the aortic valve even in the systolic phase, thereby ensuring that air is not sucked into the aorta.
The beating heart mitral valve repair via a limited right thoracotomy is a valid option in terms of less blood loss and lower risk of injury to the hazardous vascular structures and the grafts compared to a sternal reentry option. Further studies are warranted to validate the potential benefits and the limitations of this technique.
Written informed consent was obtained from the patient for publication of this Case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
We thank Taichi Sakaguchi (The Sakakibara Heart Institute of Okayama) for a technical assistance of the operation.
- Morales D, Williams E, John R: Is resternotomy in cardiac surgery still a problem?. Interact Cardiovasc Thorac Surg. 2010, 11: 277-286. 10.1510/icvts.2009.232090.View ArticlePubMedGoogle Scholar
- Atoui R, Bittira B, Morin JE, Cecere R: On-pump beating heart mitral valve repair in patients with patent bypass grafts and severe ischemic cardiomyopathy. Interact Cardiovasc Thorac Surg. 2009, 9: 138-140. 10.1510/icvts.2008.198366.View ArticlePubMedGoogle Scholar
- Romano MA, Haft JW, Pagani FD, Bolling SF: Beating heart surgery via right thoracotomy for preoperative mitral valve surgery: a safe and effective operative alternative. J Thorac Cardiovasc Surg. 2012, 144: 334-339. 10.1016/j.jtcvs.2011.09.026.View ArticlePubMedGoogle Scholar
- Suzuki Y, Pagani FD, Bolling SF: Left thoracotomy for multiple-time redo mitral valve surgery using on-pump beating heart technique. Ann Thorac Surg. 2008, 86: 466-471. 10.1016/j.athoracsur.2008.04.050.View ArticlePubMedGoogle Scholar
- Mo A, Lin H: Surgical correction of ruptured aneurysms of the sinus of valsalva using on-pump beating-heart technique. J Cardiothorac Surg. 2010, 5: 37-10.1186/1749-8090-5-37.View ArticlePubMedPubMed CentralGoogle Scholar
- Savitt MA, Singh T, Gao G, Ahmed A: Mitral valve repair on the beating perfused heart. Asian Cardiovasc Thorac Ann. 2006, 14: 252-253. 10.1177/021849230601400319.View ArticlePubMedGoogle Scholar
- Botta L, Cantata A, Frito P, Bruschi G, Trunfio S, Maneggia C, Martin EL: The role of the minimally invasive beating heart technique in reoperative valve surgery. J Card Surg. 2012, 27: 24-28. 10.1111/j.1540-8191.2011.01358.x.View ArticlePubMedGoogle Scholar
- Shu A, Zhan L, Fang H, Lv E, Chen X, Zhang M, Wang Q: Evaluation of remifentanil anesthesia for off-pump coronary artery bypass grafting surgery using heart rate variability. Exp Ther Med. 2013, 6: 253-9.PubMedPubMed CentralGoogle Scholar
- Nakanishi K, Takeda S, Kim C, Kohda S, Sakamoto A: Postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting or cardiac valve surgery: intraoperative use of landiolol. J Cardiothorac Surg. 2013, 8: 19-10.1186/1749-8090-8-19.View ArticlePubMedPubMed CentralGoogle Scholar
- Ricci M, Macedo FI, Suarez MR, Brown M, Alba J, Salerno TA: Multiple valve surgery with beating heart technique. Ann Thorac Surg. 2009, 87: 527-531. 10.1016/j.athoracsur.2008.10.030.View ArticlePubMedGoogle Scholar
- Kitamura T, Stuklis RG, Edwards J: Redo mitral valve operation via right minithoracotomy–“no touch” technique. Int Heart J. 2011, 52: 107-109. 10.1536/ihj.52.107.View ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.