Furchgott RF, Zawadzki JV: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980, 288: 373-376. 10.1038/288373a0.
Article
CAS
PubMed
Google Scholar
Marsden PA, Heng HH, Scherer SW, Stewart RJ, Hall AV, Shi XM, Tsui LC, Schappert KT: Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem. 1993, 68: 17478-17488.
Google Scholar
Radomski MW, Palmer RM, Moncada S: Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet. 1987, 2: 1057-1058.
Article
CAS
PubMed
Google Scholar
Kubes P, Suzuki M, Granger DN: Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA. 1991, 88: 4651-4655. 10.1073/pnas.88.11.4651.
Article
CAS
PubMed
PubMed Central
Google Scholar
Garg UC, Hassid A: Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest. 1989, 83: 1774-1777. 10.1172/JCI114081.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S: Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. FEBS Lett. 1993, 334: 170-174. 10.1016/0014-5793(93)81706-6.
Article
CAS
PubMed
Google Scholar
Ruvolo G, Greco E, Speziale G, Tritapepe L, Marino B, Mollace V, Nisticò G: Nitric oxide formation during cardiopulmonary bypass. Ann Thorac Surg. 1994, 57: 1055-1057. 10.1016/0003-4975(94)90249-6.
Article
CAS
PubMed
Google Scholar
Hill GE: Cardiopulmonary bypass-induced inflammation: is it important?. J Cardiothorac Vasc Anaesth. 1998, 12: 21-25.
CAS
Google Scholar
Yuan Y, Granger HJ, Zawieja DC, DeFily DV, Chilian WM: Histamine increases venular permeability via a phospholipase C-NO synthase-guanylate cyclase cascade. Am J Physiol. 1993, 264: 1734-1739.
Google Scholar
Fischer UM, Schindler R, Brixius K, Mehlhorn U, Bloch W: Extracorporeal circulation activates endothelial nitric oxide synthase in erythrocytes. Ann Thorac Surg. 2007, 84: 2000-2003. 10.1016/j.athoracsur.2007.07.034.
Article
PubMed
Google Scholar
Veldman BA, Spiering W, Doevendans PA, Vervoort G, Kroon AA, de Leeuw PW, Smits P: The Glu298Asp polymorphism of the NOS 3 gene as a determinant of the baseline production of nitric oxide. J Hypertens. 2002, 20: 2023-2027. 10.1097/00004872-200210000-00022.
Article
CAS
PubMed
Google Scholar
Wang XL, Sim AS, Wang MX, Murrell GA, Trudinger B, Wang J: Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity. FEBS Lett. 2000, 471: 45-50. 10.1016/S0014-5793(00)01356-9.
Article
CAS
PubMed
Google Scholar
Tesauro M, Thompson WC, Rogliani P, Qi L, Chaudhary PP, Moss J: Intracellular processing of endothelial nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: cleavage of proteins with aspartate vs. glutamate at position 298. Proc Natl Acad Sci USA. 2000, 97: 2832-2835. 10.1073/pnas.97.6.2832.
Article
CAS
PubMed
PubMed Central
Google Scholar
Miyamoto Y, Saito Y, Kajiyama N, Yoshimura M, Shimasaki Y, Nakayama M, Kamitani S, Harada M, Ishikawa M, Kuwahara K, Ogawa E, Hamanaka I, Takahashi N, Kaneshige T, Teraoka H, Akamizu T, Azuma N, Yoshimasa Y, Yoshimasa T, Itoh H, Masuda I, Yasue H, Nakao K: Endothelial nitric oxide synthase gene is positively associated with essential hypertension. Hypertension. 1998, 32: 3-8. 10.1161/01.HYP.32.1.3.
Article
CAS
PubMed
Google Scholar
Yoshimura M, Yasue H, Nakayama M, Shimasaki Y, Sumida H, Sugiyama S, Kugiyama K, Ogawa H, Ogawa Y, Saito Y, Miyamoto Y, Nakao K: A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm in the Japanese. Hum Genet. 1998, 103: 65-69. 10.1007/s004390050785.
Article
CAS
PubMed
Google Scholar
Shimasaki Y, Yasue H, Yoshimura M, Nakayama M, Kugiyama K, Ogawa H, Harada E, Masuda T, Koyama W, Saito Y, Miyamoto Y, Ogawa Y, Nakao K: Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction. J Am Coll Cardiol. 1998, 31: 1506-1510. 10.1016/S0735-1097(98)00167-3.
Article
CAS
PubMed
Google Scholar
Hingorani AD, Liang CF, Fatibene J, Lyon A, Monteith S, Parsons A, Haydock S, Hopper RV, Stephens NG, O’Shaughnessy KM, Brown MJ: A common variant of the endothelial nitric oxide synthase (Glu298– > Asp) is a major risk factor for coronary artery disease in the UK. Circulation. 1999, 100: 1515-1520. 10.1161/01.CIR.100.14.1515.
Article
CAS
PubMed
Google Scholar
Philip I, Plantefeve G, Vuillaumier-Barrot S, Vicaut E, LeMarie C, Henrion D, Poirier O, Levy BI, Desmonts JM, Durand G, Benessiano J: G894T polymorphism in the endothelial nitric oxide synthase gene is associated with an enhanced vascular responsiveness to phenylephrine. Circulation. 1999, 99: 3096-3098. 10.1161/01.CIR.99.24.3096.
Article
CAS
PubMed
Google Scholar
Popov AF, Hinz J, Schulz EG, Schmitto JD, Wiese CH, Quintel M, Seipelt R, Schoendube FA: The eNOS 786C/T polymorphism in cardiac surgical patients with cardiopulmonary bypass is associated with renal dysfunction. Eur J Cardiothorac Surg. 2009, 36: 651-656. 10.1016/j.ejcts.2009.04.049.
Article
PubMed
Google Scholar
Popov AF, Schulz EG, Schmitto JD, Coskun KO, Tzvetkov MV, Kazmaier S, Zimmermann J, Schöndube FA, Quintel M, Hinz J: Relation between renal dysfunction requiring renal replacement therapy and promoter polymorphism of the erythropoietin gene in cardiac surgery. Artif Organs. 2010, 34 (11): 961-968. 10.1111/j.1525-1594.2010.01108.x.
Article
PubMed
Google Scholar
Popov AF, Henker C, Schmitto JD, Wiese CH, Coskun KO, Moerer O, Danner BC, Schoendube FA, Quintel M, Hinz J: Clinical relevance of eNOS T-786C polymorphism for hospital mortality and morbidity in cardiac surgical patients. J Cardiovasc Surg (Torino). 2010, 51 (2): 265-272.
CAS
Google Scholar
Liakopoulos OJ, Dörge H, Popov AF, Schmitto JD, Cattaruzza M, Schoendube FA: Influence of eNOS gene polymorphisms (894G/T; - 786C/T) on postoperative hemodynamics after cardiac surgery. Thorac Cardiovasc Surg. 2006, 54: 233-238.
Article
CAS
PubMed
Google Scholar
Cattaruzza M, Guzik TJ, Słodowski W, Pelvan A, Becker J, Halle M, Buchwald AB, Channon KM, Hecker M: Shear stress insensitivity of endothelial nitric oxide synthase expression as a genetic risk factor for coronary heart disease. Circ Res. 2004, 95: 841-847. 10.1161/01.RES.0000145359.47708.2f.
Article
CAS
PubMed
Google Scholar
Moncada S, Higgs A: The L-arginine-nitric oxide pathway. N Engl J Med. 1993, 329: 2002-2012. 10.1056/NEJM199312303292706.
Article
CAS
PubMed
Google Scholar
Quyyumi AA, Dakak N, Andrews NP, Husain S, Arora S, Gilligan DM, Panza JA, Cannon RO: 3nd: Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis. J Clin Invest. 1995, 95: 1747-1755. 10.1172/JCI117852.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sinclair DG, Haslam PL, Quinlan GJ, Pepper JR, Evans TW: The effect of cardiopulmonary bypass on intestinal and pulmonary endothelial permeability. Chest. 1995, 108: 718-724. 10.1378/chest.108.3.718.
Article
CAS
PubMed
Google Scholar
Sellke FW, Boyle EM, Verrier ED: Endothelial cell injury in cardiovascular surgery: the pathophysiology of vasomotor dysfunction. Ann Thorac Surg. 1996, 62: 1222-1228. 10.1016/0003-4975(96)00538-3.
Article
CAS
PubMed
Google Scholar
Ruel M, Khan TA, Voisine P, Bianchi C, Sellke FW: Vasomotor dysfunction after cardiac surgery. Eur J Cardiothorac Surg. 2004, 26: 1002-1014. 10.1016/j.ejcts.2004.07.040.
Article
PubMed
Google Scholar
Osswald BR, Blackstone EH, Tochtermann U, Thomas G, Vahl CF, Hagl S: The meaning of early mortality after CABG. Eur J Cardiothorac Surg. 1999, 15: 401-407. 10.1016/S1010-7940(99)00029-9.
Article
CAS
PubMed
Google Scholar
Messaoudi N, De Cocker J, Stockman B, Bossaert LL, Rodrigus IE: Prediction of prolonged length of stay in the intensive care unit after cardiac surgery: the need for a multi-institutional risk scoring system. J Card Surg. 2009, 2: 127-133.
Article
Google Scholar