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Table 1 Clinical and hematologic characteristics of patients and univariable association to post-CABG adverse events

From: Mean platelet volume may predict early clinical outcome after coronary artery bypass grafting

Characteristic

All patients (N=205)

Adverse event

  

No (n=168)

Yes (n=37)

p value

Patient characteristics

    

  Age (years)

60.9 ± 10.3

60.4 ± 10.6

63.4 ± 8.5

0.111*

  Male

168 (82.0%)

142 (84.5%)

26 (70.3%)

0.041

  HT

129 (62.9%)

103 (61.3%)

26 (70.3%)

0.307

  HL

112 (54.6%)

94 (56.0%)

18 (48.6%)

0.419

  DM

73 (35.6%)

61 (36.3%)

12 (32.4%)

0.656

  COPD

35 (17.1%)

28 (16.7%)

7 (18.9%)

0.742

  EF (%)

55.0 (50.0-60.0)

55.0 (50.0-60.0)

50.0 (45.0-55.0)

0.010

  NYHA functional class

   

0.011

  1

146 (71.2%)

126 (75.0%)

20 (54.1%)

  2-3

59 (28.8%)

42 (25.0%)

17 (45.9%)

  EuroSCORE

0.93 (0.67-1.51)

0.84 (0.62-1.41)

1.31 (0.85-1.86)

0.001

Preoperative blood results

    

 Renal function

    

  Creatinine (mg/dl)

0.93 (0.80-1.07)

0.94 (0.81-1.08)

0.90 (0.74-0.99)

0.307

  Estimated GFR (ml/min per 1.73 m2)

94.4 ± 33.5

95.0 ± 34.5

92.1 ± 28.7

0.634*

  Hematologic paramaters

    

  Hemoglobin (g/L)

14.4 ± 1.6

14.6 ± 1.5

13.4 ± 1.5

<0.001*

  Hematocrit (%)

43.5 ± 5.2

44.1 ± 5.3

40.6 ± 4.2

<0.001*

  MCV (fL)

89.1 ± 4.9

89.1 ± 5.1

89.3 ± 4.1

0.848*

  MCH (pg)

29.7 ± 1.9

29.7 ± 1.9

29.6 ± 1.8

0.722*

  RDW (%)

13.6 (13.1-14.2)

13.5 (13.1-14.2)

13.6 (13.1-14.3)

0.274

  Platelet count (x109/L)

268 ± 67

270 ± 67

262 ± 66

0.502*

  MPV (fL)

8.50 ± 0.78

8.44 ± 0.76

8.80 ± 0.80

0.009*

  Total white cell count (x109/L)

8.27 ± 1.93

8.29 ± 2.00

8.17 ± 1.63

0.741*

  Neutrophil count (x109/L)

5.24 ± 1.64

5.23 ± 1.67

5.25 ± 1.48

0.955*

  Lymphocyte count (x109/L)

2.16 ± 0.69

2.19 ± 0.68

2.03 ± 0.72

0.211*

  Neutrophil-to-lymphocyte ratio

2.32 (1.86-3.19)

2.30 (1.81-3.15)

2.61 (1.95-3.52)

0.228

Operative data

    

  Bypass time (min)

96.7 ± 36.0

93.0 ± 35.1

113.8 ± 35.5

0.001*

  Cross-clamp time (min)

64.0 ± 25.5

62.9 ± 26.2

69.2 ± 21.8

0.173*

  Number of bypass grafts

3.0 (3.0-4.0)

3.0 (2.0-4.0)

4.0 (3.0-4.0)

0.018

Length of stay in ICU (day)

1 (1–2)

1 (1–2)

3 (1–6)

<0.001

Length of stay in hospital (day)

6 (5–7)

6 (5–7)

9 (7–18)

<0.001

  1. HT: Hypertension, HL: Hyperlipidemia, DM: Diabetes mellitus, COPD: Chronic obstructive pulmonary disease, EF: Ejection fraction, NYHA: New York Heart Association, MCV: Mean corpuscular volume, MCH: Mean corpuscular hemoglobin, RDW: Red cell distribution width, MPV: Mean platelet volume, ICU: Intensive care unit.
  2. Data are expressed as mean ± SD for normally distrubuted data and median (interquartile range) for skewed data or count (percentage) for categorical variables. * Independent-samples t test, Chi-square test, Mann–Whitney U test.