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Table 1 Clinical and hematologic characteristics of patients and univariable association to post-CABG adverse events

From: Mean platelet volume may predict early clinical outcome after coronary artery bypass grafting

Characteristic All patients (N=205) Adverse event
   No (n=168) Yes (n=37) p value
Patient characteristics     
  Age (years) 60.9 ± 10.3 60.4 ± 10.6 63.4 ± 8.5 0.111*
  Male 168 (82.0%) 142 (84.5%) 26 (70.3%) 0.041
  HT 129 (62.9%) 103 (61.3%) 26 (70.3%) 0.307
  HL 112 (54.6%) 94 (56.0%) 18 (48.6%) 0.419
  DM 73 (35.6%) 61 (36.3%) 12 (32.4%) 0.656
  COPD 35 (17.1%) 28 (16.7%) 7 (18.9%) 0.742
  EF (%) 55.0 (50.0-60.0) 55.0 (50.0-60.0) 50.0 (45.0-55.0) 0.010
  NYHA functional class     0.011
  1 146 (71.2%) 126 (75.0%) 20 (54.1%)
  2-3 59 (28.8%) 42 (25.0%) 17 (45.9%)
  EuroSCORE 0.93 (0.67-1.51) 0.84 (0.62-1.41) 1.31 (0.85-1.86) 0.001
Preoperative blood results     
 Renal function     
  Creatinine (mg/dl) 0.93 (0.80-1.07) 0.94 (0.81-1.08) 0.90 (0.74-0.99) 0.307
  Estimated GFR (ml/min per 1.73 m2) 94.4 ± 33.5 95.0 ± 34.5 92.1 ± 28.7 0.634*
  Hematologic paramaters     
  Hemoglobin (g/L) 14.4 ± 1.6 14.6 ± 1.5 13.4 ± 1.5 <0.001*
  Hematocrit (%) 43.5 ± 5.2 44.1 ± 5.3 40.6 ± 4.2 <0.001*
  MCV (fL) 89.1 ± 4.9 89.1 ± 5.1 89.3 ± 4.1 0.848*
  MCH (pg) 29.7 ± 1.9 29.7 ± 1.9 29.6 ± 1.8 0.722*
  RDW (%) 13.6 (13.1-14.2) 13.5 (13.1-14.2) 13.6 (13.1-14.3) 0.274
  Platelet count (x109/L) 268 ± 67 270 ± 67 262 ± 66 0.502*
  MPV (fL) 8.50 ± 0.78 8.44 ± 0.76 8.80 ± 0.80 0.009*
  Total white cell count (x109/L) 8.27 ± 1.93 8.29 ± 2.00 8.17 ± 1.63 0.741*
  Neutrophil count (x109/L) 5.24 ± 1.64 5.23 ± 1.67 5.25 ± 1.48 0.955*
  Lymphocyte count (x109/L) 2.16 ± 0.69 2.19 ± 0.68 2.03 ± 0.72 0.211*
  Neutrophil-to-lymphocyte ratio 2.32 (1.86-3.19) 2.30 (1.81-3.15) 2.61 (1.95-3.52) 0.228
Operative data     
  Bypass time (min) 96.7 ± 36.0 93.0 ± 35.1 113.8 ± 35.5 0.001*
  Cross-clamp time (min) 64.0 ± 25.5 62.9 ± 26.2 69.2 ± 21.8 0.173*
  Number of bypass grafts 3.0 (3.0-4.0) 3.0 (2.0-4.0) 4.0 (3.0-4.0) 0.018
Length of stay in ICU (day) 1 (1–2) 1 (1–2) 3 (1–6) <0.001
Length of stay in hospital (day) 6 (5–7) 6 (5–7) 9 (7–18) <0.001
  1. HT: Hypertension, HL: Hyperlipidemia, DM: Diabetes mellitus, COPD: Chronic obstructive pulmonary disease, EF: Ejection fraction, NYHA: New York Heart Association, MCV: Mean corpuscular volume, MCH: Mean corpuscular hemoglobin, RDW: Red cell distribution width, MPV: Mean platelet volume, ICU: Intensive care unit.
  2. Data are expressed as mean ± SD for normally distrubuted data and median (interquartile range) for skewed data or count (percentage) for categorical variables. * Independent-samples t test, Chi-square test, Mann–Whitney U test.