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Table 2 Hemodynamic parameters

From: In-vivo assessment of the morphology and hemodynamic functions of the BioValsalva™ composite valve-conduit graft using cardiac magnetic resonance imaging and computational modelling technology

 

Control (n = 2)

Patients (n = 4)

Cases

#1

#2

Mean

#1

#2

#3

#4

Mean

P-value

A mean (cm2), ascending aorta

6.5

9.7

8.1 ± 2.2

6.6

6.4

6.3

7.0

6.5 ± 0.31

0.35

D max (cm), ascending aorta

3.0

3.4

3.2 ± 0.28

2.9

2.9

2.8

3.1

2.9 ± 0.12

0.16

A sinus (cm2), aortic sinus

7.8

10.1

8.9 ± 1.6

7.7

8.8

6.8

8.5

7.9 ± 0.9

0.35

D sinus (cm), aortic sinus

3.15

3.58

3.36 ± 0.3

3.13

3.34

3.0

3.28

3.18 ± 0.15

0.35

Q max (ml/s)

682

400

541 ± 199

551

650

597

473

567 ± 75

1.0

Q mean (ml/s)

128

62

95 ± 46

99.8

107

98

81.4

96 ± 10

1.0

V max (cm/s)

238

209

223 ± 20

240

336

340

342

314 ± 49

0.06

A orifice (cm2)

4.23

4.58

4.40 ± 0.24

2.91

2.95

2.47

3.61

2.99 ± 0.47

0.06

A orifice \A sinus

0.56

0.52

0.54 ± 0.03

0.48

0.39

0.38

0.42

0.42 ± 0.04

0.06

TAWSSmax (Pa)

19.13

15.22

17.17 ± 2.7

15.15

24

12.89

17.31

17.33 ± 4.7

0.64

Compliance (mm2 • mmHg−1 • 10−3)

25.6

25

25.3 ± 0.4

9.3

12.4

18.6

10.2

12.6 ± 4.2

0.06

Distensibility (mmHg−1• 10−3)

4.06

2.6

3.33 ± 1.03

1.35

1.62

2.61

1.24

1.7 ± 0.62

0.16

Stiffness index β

0.21

0.26

0.23 ± 0.03

0.52

0.35

0.32

0.52

0.43 ± 0.11

0.06

  1. A mean : aortic cross-sectional area; D max.: aortic maximum diameter; A sinus : sinus cross-sectional area; D sinus : sinus diameter; Q max : temporal maximum flow rate; Q mean : mean flow rate throughout the cardiac cycle; V max : spatial maximum velocity at peak flow rate; A orifice : effective orifice area at peak flow rate; TAWSmax: maximum time-averaged wall shear stress.