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Table 1 Baseline characteristics according to coagulation status: Group I (low anticoagulation status) included patients with both INR below 2.0 and aPTT ratio below 1.50; Group II (adequate anticoagulation status) included patients with either INR ≥ 2.0 or aPTT ratio ≥ 1.50

From: Thromboembolic stroke in patients with a HeartMate-II left ventricular assist device – the role of anticoagulation

 

Overall

Coagulation status at the time of event

Coagulation status two weeks prior of event

 

(n = 38) median (Q1-Q3)

Group I (n = 12)

Group II (n = 26)

p

Group I (n = 8)

Group II (n = 30)

p

Age

45 (36–54)

46

44

.94

45

45

.71

Male sex (%)

25 (66 %)

7 (58 %)

18 (69 %)

.71

4 (50 %)

21 (70 %)

.41

Smoking (%)

24 (63 %)

7 (58 %)

17 (65 %)

.73

6 (75 %)

18 (60 %)

.68

Diabetes (%)

2 (5 %)

1 (8 %)

1 (4 %)

.54

0

2 (7 %)

1.0

Hypertension (%)

4 (11 %)

0

4 (15 %)

.29

0

4 (13 %)

.56

Hypercholesterolemia (%)

10 (26 %)

4 (33 %)

6 (23 %)

.69

3 (38 %)

7 (23 %)

.41

Prior MI (%)

5 (13 %)

1 (8 %)

4 (15 %)

.99

2 (25 %)

3 (10 %)

.28

Prior stroke (%)

4 (11 %)

2 (17 %)

2 (8 %)

.58

0

4 (13 %)

.56

Ischemic heart disease (%)

12 (32 %)

3 (25 %)

9 (35 %)

.71

5 (63 %)

7 (23 %)

.08

Hemoglobin

7.2 (6.5–7.9)

7.0

7.5

.23

6.4

7.4

.10

Leukocyte count

10.8 (8.3–13.9)

10.2

10.8

.75

8.5

10.8

.18

Platelet count

219 (164–296)

168

226

.34

192

226

.77

Creatinin

117 (96–150)

103

120

.11

119

114

.54

Blood urea nitrogen

10.6 (7.4–15.3)

90

11.8

.15

9.2

11.8

.31

ASAT

66 (32–192)

42

77

.24

126

62

.99

ALAT

71 (38–216)

53

77

.31

64

71

.57

LDH

481 (297–726)

354

542

.04

465

504

.68

Cardiac index

1.78 (1.50–2.01)

1.81

1.70

.77

1.86

1.69

.45

IABP treatment (%)

4 (11 %)

2 (17 %)

2 (8 %)

.58

1 (13 %)

3 (10 %)

.99

Temporary VAD (%)

4 (11 %)

2 (17 %)

2 (8 %)

.58

2 (25 %)

2 (7 %)

.19

Concomitant RVAD

0

0

0

-

0

0

-