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Two-port approached thoracoscopic carina reconstruction using natural bronchial bifurcation
© The Author(s). 2016
Received: 5 March 2016
Accepted: 30 September 2016
Published: 18 October 2016
Carina resection and reconstruction is a challenging procedure for thoracic surgeons. We describe a novel technique of thoracoscopic carina reconstruction using the natural bifurcation, following pulmonary resection of the lung neoplasm. To our knowledge, it is the first report of this kind.
A 71-year-old male diagnosed of squamous cell lung cancer received two-port approached video-assisted thoracoscopic right bilobectomy with carina resection after 2 cycles of neoadjuvant therapy. After the removal of right lower lobe and middle lobe, the 7 station lymph nodes were resected with the invaded carina and bronchial walls in an en-bloc fashion. The neocarina was reconstructed by the natural bifurcation between the right upper bronchus and the bronchus intermedius. Intraoperative blood loss was about 220 mL, and operative time was about 225 min. The postoperative course was uneventful. The pathological TNM stage was pT3N2M0, IIIA. Adjuvant chemotherapy using gemcitabine and cisplatin was administered for 4 cycles. Follow-up 6 months after surgery confirmed no stenosis and no signs of local recurrence by bronchoscopy and CT scan.
We consider that the surgical procedure described here is a new alternative strategy for carina resection and reconstruction in the similar situation. The minimally invasive method is safe and effective for this challenging operation.
Carina resection and reconstruction is a challenging procedure for thoracic surgeons. The surgical method is widely dependent on the location and extent of the invasion. Here we present a minimally invasive surgical technique to perform this procedure by using the natural bronchial bifurcation for the neocarina. To our knowledge, it is the first report of this kind.
During the operation, the lung was first retracted anteriorly to mobilize the posterior hilum. Through detection, the subcarinal, the right posterior hilar and interlobar lymph nodes were found enlarged and fused together, highly attaching to the inner wall of left main bronchus, the carina, the inner wall of right main bronchus and the bronchus intermedius, which matched the preoperative evaluation. To achieve R0 resection, we decided to perform bilobectomy of right lower lobe and right middle lobe with carina resection and reconstruction.
The reconstruction was made by 3–0 polene with running sutures. To decrease the tension, each one of the stitches was sutured for only 1 to 2 cm long. The closure of the cartilage portion was performed firstly. Then the left main bronchial semicircular defect was patched, using the residual semicircular wall of the right bronchus (Fig. 3b). The membranous portion was sutured at last. To avoid the airways instability, the spare cartilage tissue of the right bronchus was constrictively sutured onto the membranous portion of neocarina, and served as osseous support (Fig. 3c). The bifurcation between the right upper bronchus and the bronchus intermedius was used as the neocarina (Fig. 3d).
During the reconstruction, when the operator was resecting and suturing the bronchus or the carina, the anesthetist loosened the tube balloon and retracted the endotracheal tube above the carina, which spared the space for surgical manipulation. A little airway leakage in seconds was allowed and the patient would tolerate it well. Before the operator was knotting, the anesthetist inserted the tube back to its original position with the help of operator’s guide. During the reconstruction, no apnoea was used. After reconstruction, no air leakage was noted with a sustained airway pressure of 25 cmH2O. Coverage of anastomosis was made by the pericardium fat. Frozen sections of resection margins were negative. Intraoperative blood loss was about 220 mL, and operative time was about 225 min.
The postoperative course was uneventful. The chest tube was removed on postoperative day 4. The patient was discharged on postoperative day 7. The final pathologic examination confirmed the tumor invasion of the carina, and revealed metastases in the 4R, 7, 10R, 11R stations. Adjuvant chemotherapy using gemcitabine and cisplatin was administered for 4 cycles. Follow-up 6 months after surgery confirmed no stenosis and no signs of local recurrence by bronchoscopy and CT scan (Additional file 1: Figure S2).
The carina resection and reconstruction is indicated to the invasion of lower trachea or carina by malignance . For non-small cell lung cancer, the overall survival of 5 years for carina resection ranges from 28.5 to 66.3 % [2–5]. The technique is various according to extent of invasion. In this case, the invasion is induced by the metastasized lymph nodes, which is a less common situation. During the operation, the invaded carina was resected and reconstructed by the natural bifurcation. This novel technique help the neocarina avoid neither a redundant suture nor an artificial reconstruction. Meanwhile, it reserves a functional carina and the stability of airways.
Before surgery, we used computed rapid prototyping to evaluate the invasion of the carina and the bronchus. The result showed the invaded wall was less than 50 % of airway circumference, which technically supported the performance of the reconstruction plan . The rapid prototyping technique has just been used in thoracic surgery recently. Several researches report its advantage in pulmonary segmentectomy [7, 8]. In this case, the result of rapid prototyping was conformed to the intraoperative detection, which indicates the probability to use this technique in the surgery of central lung neoplasm.
We consider that the surgical procedure described here is a new alternative strategy for carina resection and reconstruction in the similar situation. The minimally invasive method combined with rapid prototyping is safe and effective for this challenging operation.
All the authors state that there is no grant, funding, financial support or technical or other assistance in this article.
Availability of data and material
WJ performed the operation; YZ, TQ, and BF were the surgery assistants; JS performed the anesthesia; TQ drafted the manuscript. YX helped to draft the manuscript. All authors read and approved the final manuscript.
All the authors state that there is no conflict and/or competing interest. There is no any prior or related publications, and prior abstract/poster presentation.
Consent for publication
Written informed consent was obtained from the patient for publication of this report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
Ethics approval and consent to participate
The ethics committee of Qingdao University has consented the ethics approval and the participation for this case report. All authors consent to publish this manuscript.
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- Grillo HC. Carinal reconstruction. Ann Thorac Surg. 1982;34:356–73.View ArticlePubMedGoogle Scholar
- Yamamoto K, Miyamoto Y, Ohsumi A, et al. Surgical results of carinal reconstruction: an alternative technique for tumors involving the tracheal carina. Ann Thorac Surg. 2007;84(1):216–20.View ArticlePubMedGoogle Scholar
- Macchiarini P, Altmayer M, Go T, et al. Technical innovations of carinal resection for nonsmall-cell lung cancer. Ann Thorac Surg. 2006;82(6):1989–97. discussion 1997.View ArticlePubMedGoogle Scholar
- Shin S, Park JS, Shim YM, et al. Carinal resection and reconstruction in thoracic malignancies. J Surg Oncol. 2014;110(3):239–44.View ArticlePubMedGoogle Scholar
- de Perrot M, Fadel E, Mercier O, et al. Long-term results after carinal resection for carcinoma: does the benefit warrant the risk? J Thorac Cardiovasc Surg. 2006;131(1):81–9.View ArticlePubMedGoogle Scholar
- He WX, Song N, Liu M, et al. Bronchoplastic closure as an alternative approach for tracheal reconstruction following resection of a massive tracheal tumour. Interact Cardiovasc Thorac Surg. 2015;21(2):263–5.View ArticlePubMedGoogle Scholar
- Akiba T, Nakada T, Inagaki T. Three-dimensional pulmonary model using rapid-prototyping in patient with lung cancer requiring segmentectomy. Ann Thorac Cardiovasc Surg. 2014;20(Suppl):490–2.View ArticlePubMedGoogle Scholar
- Nakada T, Akiba T, Inagaki T, et al. Thoracoscopic anatomical subsegmentectomy of the right S2b + S3 using a 3D printing model with rapid prototyping. Interact Cardiovasc Thorac Surg. 2014;19(4):696–8.View ArticlePubMedGoogle Scholar