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Table 5 Effect of demographic variables on results as dichotomised by sVCAM-1 cut off of 763.5 ng/L (corresponds to a sensitivity of 50% and a specificity of 95.45%, with 84.38% of patients correctly classified)

From: Pre-operative serum VCAM-1 as a biomarker of atrial fibrillation after coronary artery bypass grafting

Continuous Variables

Coefficient

SE

p

95% CI

Pre-operative demographics

Age (yrs)

0.053

0.052

0.312

−0.049, 0.155

BMI (kg/m2)

−0.134

0.172

0.436

−0.471, 0.203

Height (m)

−0.229

4.151

0.956

−8.36, 7.91

Weight (kg)

−0.047

0.050

0.351

−0.146, 0.052

Bypass time

0.010

0.026

0.708

−0.041, 0.061

X-clamp time

−0.011

0.025

0.673

−0.060, 0.038

White cell count

−0.301

0.488

0.537

−1.257, 0.655

Platelet count

−0.029

0.031

0.352

−0.090, 0.032

Dichotomous Variables

sVCAM1 < 763.5 (n = 26)

sVCAM1 ≥ 763.5 (n = 6)

Chi^2

p-value

Gender (M)

75%

60%

0.4661

0.495

MI

32%

0%

1.7676

0.184

PVD

8%

0%

0.3437

0.558

Stroke/TIA

8%

25%

1.0745

0.300

Hypertension

68%

100%

1.768

0.184

Hypercholesterolaemia

88%

100%

0.5354

0.464

Family History

64%

25%

2.1622

0.141

Diabetes

- On Insulin

48%

24%

75%

50%

1.0067

1.1669

0.316

0.280

Smoking

20%

0%

0.9667

0.326

Alcohol >10u per week

62.5%

25%

1.9688

0.161

LMS

31.8%

25%

0.0739

0.786

Pre-operative medications

Beta-blocker use

73.9%

50%

0.9345

0.334

Statin use

100%

87.0%

0.5870

0.444

Aspirin use

100%

91.3%

0.3757

0.540

Post-op Atrial fibrillation

20%

75%

7.143

0.008**

  1. The asterisks denote standard statistical notation for significance. ** - p < 0.005