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Table 4 Lung nodule histopathology

From: Hybrid operating room with ceiling mounted imaging system assisted pre-operative and intra-operative lung nodule localization for thoracoscopic resections: a 5-year case series

Lung nodule histopathology with correlation to radiological characteristic

Histology

Radiological Characteristic

All Nodules (n = 36)

n (%)

Solid (n = 13)

n (%)

Mixed or Ground-glass (n = 23)

n (%)

Primary Lung Cancer or Pre-Malignant Lesions

31 (86.0%)

Invasive Adenocarcinoma: 24

Invasive Mucinous Adenocarcinoma: 2

Minimally Invasive Adenocarcinoma: 3

Atypical Adenomatous Hyperplasia: 2

8 (62.0%)

23 (100.0%)

Metastatic Lesions

2 (7.0%)

Leiomyosarcoma: 1

Thymoma: 1

2 (15.0%)

0

Benign Lesions

3 (7.0%)

Scar Tissue: 2

Intraparenchymal Lymph Node: 1

3 (23.0%)

0

Statistical analyses of lung nodule histopathology

Histology

All Nodules (n = 36)

n (%)

Solid (n = 13)

n (%)

Mixed or Ground-glass (n = 23)

n (%)

p-Value

Malignant

Yes

33 (92.0%)

10 (77.0%)

23 (100.0%)

0.04§

No

3 (8.0%)

3 (23.0%)

0

Parenchymal resection margins of primary lung cancer, pre-malignant lesions and metastatic lesions

 

Mean (SD)

Mean Difference (95% CI)

t-Statistic (df)

p-Value

Total Nodules (n = 32)†

Pre-op Localization (n = 14)†

Intra-op Localization (n = 18)

Parenchymal resection margins (mm)

9.8 (5.43)

9.0 (4.76)

10.4 (5.97)

 − 1.39 ( − 5.26 to 2.48)

 − 0.73 (30)

0.47

  1. §Fisher’s Exact Test
  2. †Parenchymal resection data was not available for one pre-malignant nodule in the pre-operative group