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Table 2 Clinical findings in patients with TNET

From: Analysis of 25 surgical cases of thymic neuroendocrine tumors and thymic carcinoma

 

Age (years) /Sex

Histology

Tumor

size

(mm)

Preoperative therapy

Resection

status

Combined resection

Masaoka stage

Postoperative therapy

Relapse site

Prognosis

(Survival time, days)

CT

RT

(Gy)

Effect

CT

RT

(Gy)

1

58 M

Combined*

45

-

-

 

R2

-

4a

-

-

-

A(51)

2

51 M

LCNEC

78

-

-

 

R0

L, PC, PN

2

-

-

Local

A(672)

3

83 M

Ac

104

-

-

 

R0

PC

2

-

-

-

A(233)

4

68 M

LCNEC

75

-

-

 

R0

L PC

4a

ADOC

PRT

Distant

D(1410)

5

45 F

Ac

62

CDDP + VP-16

40

PR

R0

PC

3

SST, Ev

-

Distant

A(2912)

6

61 M

Poorly

65

-

-

 

R0

-

2

CDDP + VP-16

-

-

A(2994)

7

70 M

Ac

90

-

-

 

R0

BCV, PC

4b

-

-

Local

A(3587)

8

54 M

SCC

65

-

-

 

R0

L

3

CDDP + VP-16

50 Gy

Distant

D(3630)

9

50 M

SCC

34

CDDP + VP-16 + ADM

45

PR

R0

-

3

-

-

-

A(4870)

  1. *Combined: Thymic carcinoma with neuroendocrine carcinoma components
  2. TNET, thymic neuroendocrine tumors; M, male; F, female; LCNEC, large cell neuroendocrine carcinoma; Ac, atypical carcinoid; SCC, small cell carcinoma; Poorly, poorly differentiated thymic neuroendocrine carcinoma; CT, chemotherapy; RT, radiotherapy; CDDP, cisplatin; VP-16, etoposide; ADM, doxorubicin hydrochloride; PR, partial response; PRT, palliative radiotherapy; ADOC, doxorubicin hydrochloride + cisplatin + vincristine sulfate + cyclophosphamide; L, lung; PC, pericardium; PN, phrenic nerve; BCV, brachiocephalic vein; SST, somatostatin; Ev, everolimus; A, alive; D, dead