Table 5 Summary of studies related to TC and TNET
From: Analysis of 25 surgical cases of thymic neuroendocrine tumors and thymic carcinoma
Author (published year) | No. | Pathology | Surgery case | R0 Resection rate(%) | Survival |
|---|---|---|---|---|---|
our study | 25 | TC:16[Sq(n = 15),Adsq(n = 1)] TNET:9[Ac(n = 3),LCNEC(n = 2),SCC(n = 2), other(n = 2)] | 100%(25/25) | TC:81 TNET:88 | 5yOS/5yDFS TC:58.9/ 57. % TNET:87.5/ 75% |
Kondo [15] (2003)* | 1320 | TC:186 [Sq1(n = 115),und(n = 27),SCC(n = 16),Ad(n = 5) ,Adsq(n = 4),other(n = 7)] TCD:41 [Tc or Ac(n = 41)] Thy:1093 | TC:71.9% TCD:92.5% Thy:97% | NA | 5yOS TC:84.4% TCD:84.4% Thy:94.4% |
Benny [16] (2015) | 229 | TC:176 TNET:53 | TC + TNET Resection 93%/ Debulking7% | NA | mOS TC:85 m TNET:117 m |
Filosso [17] (2016) | 1247 | TC:1042[Sq79%,other21%] TNET:205[Tc(n = 49),Ac(n = 71), LCNECorSCC(n = 49)] | 100% (1227/1227) | TC:60 TNET:54 | 5yOS/10yOS/5yRFS TC:60/40/35% TNET:68,1/39,5/34% |
Zhao [18] (2017) | 343 | TC:287 TCD:56 (Tc or Ac) | TC:90.6% TCD:86.4% | TC:45.6 TCD:53.6 | 5yOS/5yDFS TC:60.7/41.1% TCD:80.7/37.6% |
Wen [19] (2018) | 3947 | TC:886 [well8.1%,Mod13.6%,Poor64.6%,Und13.6%] TNET:293 [well41.5%,Mod25.8,%Poor21.4%,Und11.3%] Thy:2788 | TC:58.7% TNET:66.9% Thy:78.2% | NA | TC: NA TNET: mCSS82.9 m, mOS101.9 m |
Song [20] (2019) | 362 | TC:240 TNET:122 | TC + TNET Surgery of primary site 73.2% | NA | MST TC:92 m TNET:52 m |
Bakhos [21](2020) | 1489 | TC:80.2% TNET:19.8% | TC:55.3% TNET:58.3% | NA | 5yOS TC:52% TNET:62% |